There is a new provider for Simple.Data available via NuGet that will allow you to consume Sqlite databases. Both in memory and file based database are supported. This initial release has some warts in the API, but is usable. It is currently being used in the NerdBeers project for testing support. I plan to buff out the warts over the next few versions.
Be sure to watch full screen or download the original HD source.
Check out the various sources: